Mental wellbeing / probiotics
probiotics
Evidence for mental wellbeing, scored from the published research.
anxiety
promising60/100 Evidence ScoreConfidence: moderate5 studies2 RCTs
Multiple human studies report a positive effect.
- 5 human studies (5,936 participants across the 4 with counts recorded; 1 review/meta-analysis not counted individually)
- Studies disagree with each other
References (5)
- The Effect of Prebiotics and Probiotics on Levels of Depression, Anxiety, and Cognitive Function: A Meta-Analysis of Randomized Clinical Trials.meta-analysis · Brain and behavior · 2025
- A systematic review of the effects of probiotics on depression and anxiety: an alternative therapy?systematic review · Ciencia & saude coletiva · 2021
- Efficacy of probiotics on anxiety-A meta-analysis of randomized controlled trials.meta-analysis · Depression and anxiety · 2018
- Psychobiotic Lactobacillus plantarum JYLP-326 relieves anxiety, depression, and insomnia symptoms in test anxious college via modulating the gut microbiota and its metabolism.randomized controlled trial (RCT) · Frontiers in immunology · 2023
- Effects of Probiotics on Anxiety, Stress, Mood and Fitness of Badminton Players.randomized controlled trial (RCT) · Nutrients · 2021
mood
reported, but evidence is limited42/100 Evidence ScoreConfidence: low1 study1 RCT
There are positive reports, but the evidence in humans is still limited.
- 1 human study (63 participants total)
- Still unknown: few studies so far
References (1)
- Probiotic Supplementation Improves Cognitive Function and Mood with Changes in Gut Microbiota in Community-Dwelling Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial.randomized controlled trial (RCT) · The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
Evidence Scores are computed mechanically from the published research (PubMed / Semantic Scholar / OpenAlex): study design, participant numbers, and consistency across studies. An LLM is used only to extract study data, never to decide a score.
This is research-based information, not medical advice, and not a diagnosis. Consult a qualified professional about your own situation.