気分が上がらない日が続くとき

The Effects of Combined Scutellaria and Saffron Supplementation on Mood Regulation in Participants with Mild-to-Moderate Depressive Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study.

• 参加者 180人
• 軽度から中等度のうつ症状がある参加者 180名

原文よりThe results confirmed the beneficial effects of saffron extract on depressive and anxious symptoms, as well as its role in improving sleep quality.

Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial.

• 参加者 56人
• 気分が低下している、あるいは不安やストレスを感じている健康な成人 56名

原文よりParticipants who received the saffron extract reported reduced depression scores and improved social relationships at the end of the study.

affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial.

• 参加者 128人
• 気分が低いと自己申告した健康な成人 128名
• affron® (28mg/day, 22mg/day) 4週間

原文よりAnalysis indicated a significant decrease in negative mood and symptoms related to stress and anxiety at a 28mg/day dose (with a significant difference between 28mg/day and placebo on the POMS Total Mood Disturbance scale, p<0.001, d=-1.10), but no treatment effect at the 22mg/day dose.

The role of omega-3 fatty acids in mood disorders.

• 単極性および双極性うつ病の患者
• 4-16週間

原文よりIn four out of the seven studies conducted in depressed individuals and in two out of the five studies in bipolar patients, individuals have reported a positive outcome following supplementation with ethyl-eicosapentaenoic acid or fish oil containing long-chain omega-3 PUFA.

Efficacy of omega-3 fatty acids in mood disorders - a systematic review and metaanalysis.

• 参加者 1,840人
• 気分障害患者

原文よりThe available evidence suggests that omega-3 fatty acids are a potential treatment of depressive disorders, but not mania.